Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | KRAS | P01116 | 3/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.34 |
| ▸ | AXL | P30530 | 9/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23715887 | 0.92 | MEN1 (0.34) | P2RY12HDAC1EGLN1AXL | |
| SCHEMBL26633248 | 0.88 | KRAS (0.44) | KRASSOS1 | |
| SCHEMBL30111419 | 0.88 | KRAS (0.44) | KRASSOS1 | |
| SCHEMBL30111429 | 0.87 | KRAS (0.40) | HDAC1EGLN1KRASSOS1AXL | |
| SCHEMBL30111530 | 0.87 | KRAS (0.48) | KRASSOS1 | |
| SCHEMBL30111448 | 0.87 | HDAC1 (0.35) | HDAC1EGLN1KRASSOS1AXL | |
| SCHEMBL23715770 | 0.87 | HDAC1 (0.35) | HDAC1EGLN1KRASSOS1AXL | |
| SCHEMBL23702666 | 0.87 | KRAS (0.40) | HDAC1EGLN1KRASSOS1AXL | |
| SCHEMBL23702511 | 0.87 | KRAS (0.48) | KRASSOS1 | |
| SCHEMBL23702653 | 0.87 | KRAS (0.48) | KRASSOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021152149-A1 | RAS INHIBITORS AND METHODS OF USING THE SAME | JAZZ PHARMACEUTICALS IRELAND LIMITED (IE) | 2021-08-05 | — | — | WO | disclosed |