Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MME | P08473 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA3 | P07451 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5043330 | 0.86 | SLC1A3 (0.54) | KMT2AMEN1OPRK1PKMSCN9A | |
| SCHEMBL5043331 | 0.86 | SLC1A3 (0.54) | KMT2AMEN1OPRK1PKMSCN9A | |
| SCHEMBL5047819 | 0.85 | F2 (0.61) | KMT2AMEN1 | |
| SCHEMBL5047815 | 0.85 | F2 (0.61) | KMT2AMEN1 | |
| SCHEMBL12168556 | 0.84 | CA12 (0.61) | KMT2AMEN1MMEGPR88ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5045157 | 0.84 | F2 (0.60) | KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL5045156 | 0.84 | F2 (0.60) | KMT2AMEN1 | |
| SCHEMBL4793272 | 0.83 | KMT2A (0.56) | KMT2AMEN1PKMMMP8GPR88 | |
| SCHEMBL31621324 | 0.83 | PKM (0.55) | KMT2AMEN1OPRK1PKMMMP8 | |
| Hydrochloric Acid SCHEMBL4222545 | 0.82 | KMT2A (0.51) | KMT2AMEN1GAAPKMMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |