Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.31 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
| ▸ | PNMT | P11086 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23715869 | 0.89 | SMN1; SMN2 (0.33) | PTPN7DUSP3SMN1; SMN2KMT2AMCL1 | |
| SCHEMBL23715780 | 0.87 | IDO1 (0.42) | KMT2AIDO1NPFFR2CRHBPCRHR2 | |
| SCHEMBL23716362 | 0.78 | IDO1 (0.39) | SMN1; SMN2IDO1ALDH1A1L3MBTL1 | |
| SCHEMBL23715988 | 0.76 | IDO1 (0.40) | IDO1CA2L3MBTL1 | |
| SCHEMBL23715862 | 0.76 | IDO1 (0.41) | KMT2AIDO1NPFFR2CRHBPCRHR2 | |
| SCHEMBL23716370 | 0.75 | IDO1 (0.44) | KMT2AIDO1NPFFR2CRHBPCRHR2 | |
| SCHEMBL23716186 | 0.75 | IDO1 (0.41) | KMT2AIDO1NPFFR2CRHBPCRHR2 | |
| SCHEMBL31480988 | 0.75 | CA2 (0.47) | SMN1; SMN2MCL1ALDH1A1CA2 | |
| SCHEMBL5263646 | 0.75 | CA2 (0.47) | SMN1; SMN2MCL1ALDH1A1CA2 | |
| SCHEMBL23716176 | 0.74 | IDO1 (0.40) | IDO1NPFFR2CRHBPCRHR2PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |