Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20651981 | 0.84 | — | — | |
| SCHEMBL24179436 | 0.84 | HTR3E (0.32) | — | |
| SCHEMBL21217852 | 0.83 | HDAC3 (0.30) | HDAC3HDAC1HDAC2 | |
| SCHEMBL21217720 | 0.83 | HDAC3 (0.31) | HDAC3HDAC1HDAC2 | |
| SCHEMBL24934066 | 0.82 | HDAC3 (0.30) | HDAC3HDAC1HDAC2 | |
| SCHEMBL24610241 | 0.82 | HDAC3 (0.30) | HDAC3HDAC1HDAC2 | |
| SCHEMBL24934037 | 0.82 | HDAC3 (0.30) | HDAC3HDAC1HDAC2 | |
| SCHEMBL15108824 | 0.81 | MAPT (0.57) | KDM4EGAAMAPTHDAC3HDAC1 | |
| SCHEMBL21230650 | 0.79 | — | — | |
| SCHEMBL24610331 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021152149-A1 | RAS INHIBITORS AND METHODS OF USING THE SAME | JAZZ PHARMACEUTICALS IRELAND LIMITED (IE) | 2021-08-05 | — | — | WO | disclosed |