Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.47 |
| ▸ | NPC1 | O15118 | 7/20 | 0.47 |
| ▸ | RAB9A | P51151 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15822145 | 0.86 | CYP3A4 (0.45) | SMN1; SMN2NPC1RAB9AMAPTHPGD | |
| SCHEMBL11151377 | 0.82 | CYP3A4 (0.48) | SMN1; SMN2NPC1RAB9AMAPTHPGD | |
| SCHEMBL29647925 | 0.81 | CYP3A4 (0.48) | SMN1; SMN2NPC1RAB9AMAPTMEN1 | |
| Toluene SCHEMBL28840552 | 0.80 | CYP3A4 (0.50) | SMN1; SMN2NPC1RAB9AMAPTHPGD | |
| SCHEMBL8040015 | 0.79 | PTPN1 (0.61) | NPC1RAB9AMEN1KMT2ATDP1 | |
| Toluene SCHEMBL28033107 | 0.78 | NAPRT (0.60) | SMN1; SMN2NPC1RAB9AMAPTHPGD | |
| Toluene SCHEMBL28333295 | 0.78 | NAPRT (0.60) | SMN1; SMN2NPC1RAB9AMAPTHPGD | |
| SCHEMBL93286 | 0.78 | CYP3A4 (0.56) | SMN1; SMN2NPC1RAB9AMAPTHPGD | |
| SCHEMBL12604117 | 0.77 | TSHR (0.65) | SMN1; SMN2NPC1RAB9AMAPTMEN1 | |
| SCHEMBL23716619 | 0.77 | CYP3A4 (0.44) | SMN1; SMN2NPC1RAB9AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3500611-B1 | PROCESS FOR THE SYNTHESIS OF POLYOXAZOLIDINONE COMPOUNDS | COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) | 2021-08-11 | — | — | EP | claimed |