Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | STAT1 | P42224 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29647925 | 0.95 | CYP3A4 (0.48) | CYP3A4TSHRTRPA1TDP1SMN1; SMN2 | |
| SCHEMBL19876727 | 0.87 | CYP3A4 (0.50) | CYP3A4TSHRTRPA1TDP1SMN1; SMN2 | |
| Dimethylamine SCHEMBL28015585 | 0.83 | CYP3A4 (0.56) | CYP3A4TSHRTRPA1TDP1SMN1; SMN2 | |
| SCHEMBL93286 | 0.81 | CYP3A4 (0.56) | CYP3A4TSHRTRPA1TDP1SMN1; SMN2 | |
| Hydrogen Sulfide SCHEMBL27351182 | 0.79 | CYP3A4 (0.54) | CYP3A4TSHRTRPA1TDP1SMN1; SMN2 | |
| Toluene SCHEMBL2054280 | 0.78 | TSHR (0.44) | CYP3A4TSHRTRPA1TDP1SMN1; SMN2 | |
| SCHEMBL11151377 | 0.77 | CYP3A4 (0.48) | CYP3A4TSHRTRPA1TDP1SMN1; SMN2 | |
| SCHEMBL23716618 | 0.77 | SMN1; SMN2 (0.47) | TSHRTDP1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL28301007 | 0.77 | CYP3A4 (0.61) | CYP3A4TSHRTRPA1TDP1MAPK1 | |
| SCHEMBL20893292 | 0.77 | ALDH1A1 (0.61) | CYP3A4TSHRTRPA1TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11326018-B2 | Process for the synthesis of polyoxazolidinone compounds | COVESTRO DEUTSCHLAND AG (DE) | 2022-05-10 | — | — | US | disclosed |
| US-20210284785-A1 | PROCESS FOR THE SYNTHESIS OF POLYOXAZOLIDINONE COMPOUNDS | COVESTRO DEUTSCHLAND AG (DE) | 2021-09-16 | — | — | US | disclosed |
| EP-3500611-B1 | PROCESS FOR THE SYNTHESIS OF POLYOXAZOLIDINONE COMPOUNDS | COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) | 2021-08-11 | — | — | EP | disclosed |