Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | PDE2A | O00408 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | YTHDF3 | Q7Z739 | 1/20 | 0.41 |
| ▸ | YTHDF1 | Q9BYJ9 | 1/20 | 0.41 |
| ▸ | YTHDF2 | Q9Y5A9 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid Methyl Ester SCHEMBL29809733 | 0.83 | PARP1 (0.41) | DDB1CRBNGAASMN1; SMN2HTT | |
| Formic Acid Methyl Ester SCHEMBL28826693 | 0.83 | PARP1 (0.41) | DDB1CRBNGAASMN1; SMN2HTT | |
| SCHEMBL29809619 | 0.78 | DDB1 (0.38) | DDB1CRBNGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL29809817 | 0.77 | PDE2A (0.39) | DDB1CRBNGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL3988562 | 0.73 | SMN1; SMN2 (0.54) | SMN1; SMN2HTTPDE2AYTHDF3YTHDF1 | |
| SCHEMBL1535571 | 0.73 | PDE2A (0.53) | PDE2A | |
| SCHEMBL16867827 | 0.72 | PDE2A (0.52) | PDE2A | |
| SCHEMBL15660792 | 0.70 | JAK2 (0.44) | NPC1PDE2ALMNACYP1A2TMIGD3 | |
| SCHEMBL5935763 | 0.70 | — | — | |
| SCHEMBL29107895 | 0.70 | KDM4E (0.38) | DDB1CRBNGAASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230128972-A1 | Anat Inhibitors and Methods of Use Thereof | Atomwise Inc. | 2023-04-27 | — | — | US | disclosed |
| WO-2021155253-A1 | ANAT INHIBITORS AND METHODS OF USE THEREOF | Atomwise Inc. (US) | 2021-08-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230128972-A1 | Anat Inhibitors and Methods of Use Thereof | AANAT, CHAT, NAT1 | DDB1 3513/4885CRBN 2335/4885GAA 33/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.