Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 4/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27190515 | 0.91 | USP2 (0.42) | USP2SMN1; SMN2USP30RORCHDAC2 | |
| SCHEMBL29985644 | 0.91 | USP2 (0.42) | USP2SMN1; SMN2USP30RORCHDAC2 | |
| SCHEMBL3250470 | 0.84 | USP2 (0.49) | USP2SMN1; SMN2HDAC2HDAC1HPGD | |
| SCHEMBL21811041 | 0.81 | USP2 (0.45) | USP2SMN1; SMN2USP30RORCHDAC2 | |
| SCHEMBL31716895 | 0.80 | USP2 (0.43) | USP2SMN1; SMN2RORCHPGDEPHX2 | |
| SCHEMBL17163075 | 0.79 | USP2 (0.46) | USP2SMN1; SMN2USP30HDAC2CYP11B2 | |
| SCHEMBL358661 | 0.79 | USP2 (0.46) | USP2SMN1; SMN2USP30HDAC2CYP11B2 | |
| SCHEMBL15797058 | 0.79 | USP2 (0.46) | USP2SMN1; SMN2USP30HDAC2CYP11B2 | |
| SCHEMBL31567039 | 0.78 | USP2 (0.42) | USP2SMN1; SMN2USP30RORCHDAC2 | |
| SCHEMBL745050 | 0.77 | USP2 (0.41) | USP2SMN1; SMN2USP30RORCHDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858349-A1 | NITROGEN-CONTAINING SPIRO-RING COMPOUND AND MEDICINAL USE OF SAME | Japan Tobacco Inc. (JP) | 2021-08-04 | — | — | EP | disclosed |