SCHEMBL21811041

SCHEMBL21811041

CC(C)(C)OC(=O)N1CCC(N)(F)C1

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
HDAC2 Q92769 2/20 0.41
CYP11B2 P19099 1/20 0.40
USP30 Q70CQ3 2/20 0.39
RORC P51449 3/20 0.39
HPGD P15428 1/20 0.39
SCD5 Q86SK9 1/20 0.39
HDAC1 Q13547 1/20 0.38
EPHX2 P34913 1/20 0.38
ACACB O00763 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8254018 0.90 USP2 (0.51) USP2SMN1; SMN2HDAC2HPGDHDAC1
SCHEMBL475749 0.83 USP2 (0.47) USP2SMN1; SMN2HDAC2CYP11B2USP30
SCHEMBL30254327 0.81 USP2 (0.46) USP2SMN1; SMN2HDAC2CYP11B2USP30
SCHEMBL358661 0.81 USP2 (0.46) USP2SMN1; SMN2HDAC2CYP11B2USP30
SCHEMBL17163075 0.81 USP2 (0.46) USP2SMN1; SMN2HDAC2CYP11B2USP30
SCHEMBL16590451 0.81 USP2 (0.46) USP2SMN1; SMN2HDAC2CYP11B2USP30
SCHEMBL12445300 0.81 USP2 (0.46) USP2SMN1; SMN2HDAC2CYP11B2USP30
SCHEMBL15797058 0.81 USP2 (0.46) USP2SMN1; SMN2HDAC2CYP11B2USP30
SCHEMBL23717650 0.81 USP2 (0.42) USP2SMN1; SMN2HDAC2CYP11B2USP30
SCHEMBL29985644 0.81 USP2 (0.42) USP2SMN1; SMN2HDAC2CYP11B2USP30

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020054788-A1 IMIDAZOPYRIDINONE COMPOUND キッセイ薬品工業株式会社 2020-03-19 WO disclosed