Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 20/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20203320 | 0.78 | TRPA1 (1.00) | TRPA1 | |
| SCHEMBL21354120 | 0.78 | TRPA1 (1.00) | TRPA1 | |
| SCHEMBL23718437 | 0.72 | TRPA1 (0.50) | TRPA1 | |
| SCHEMBL22194525 | 0.68 | TRPA1 (1.00) | TRPA1 | |
| SCHEMBL22194527 | 0.68 | TRPA1 (1.00) | TRPA1 | |
| SCHEMBL22210524 | 0.67 | TRPA1 (0.78) | TRPA1 | |
| SCHEMBL20187589 | 0.66 | TRPA1 (1.00) | TRPA1 | |
| SCHEMBL20203317 | 0.63 | TRPA1 (1.00) | TRPA1 | |
| SCHEMBL21354185 | 0.63 | TRPA1 (1.00) | TRPA1 | |
| SCHEMBL21354124 | 0.61 | TRPA1 (1.00) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3544979-B1 | OXADIAZOLONES AS TRANSIENT RECEPTOR POTENTIAL CHANNEL INHIBITORS | HOFFMANN LA ROCHE (CH) | 2021-08-04 | — | — | EP | disclosed |