Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29314886 | 0.79 | — | — | |
| SCHEMBL14868264 | 0.76 | KDM1A (0.44) | KDM1A | |
| SCHEMBL22166727 | 0.75 | — | — | |
| SCHEMBL3077084 | 0.73 | — | — | |
| SCHEMBL26333133 | 0.73 | KDM1A (0.46) | KDM1A | |
| SCHEMBL26333119 | 0.70 | EPHX1 (0.52) | KDM1A | |
| SCHEMBL29418156 | 0.70 | ALDH1A1 (0.32) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| SCHEMBL17835879 | 0.70 | ALDH1A1 (0.32) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| SCHEMBL862169 | 0.69 | — | — | |
| SCHEMBL244973 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021154664-A1 | 1H-PYRAZOLO[4,3-d]PYRIMIDINE COMPOUNDS AS TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-08-05 | — | — | WO | disclosed |