Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 5/20 | 0.46 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CDA | P32320 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | EIF4E | P06730 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TOP1 | P11387 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22933055 | 0.79 | SMN1; SMN2 (0.41) | SLC5A2MAPTCDALMNASMN1; SMN2 | |
| SCHEMBL15279674 | 0.76 | SLC5A2 (0.45) | SLC5A2SLC5A1MAPTCDALMNA | |
| SCHEMBL16138515 | 0.76 | SLC5A2 (0.45) | SLC5A2SLC5A1MAPTCDALMNA | |
| SCHEMBL19464856 | 0.76 | SLC5A2 (0.45) | SLC5A2SLC5A1MAPTCDALMNA | |
| SCHEMBL16310914 | 0.76 | SLC5A2 (0.45) | SLC5A2SLC5A1MAPTCDALMNA | |
| SCHEMBL19807517 | 0.76 | SLC5A2 (0.45) | SLC5A2SLC5A1MAPTCDALMNA | |
| SCHEMBL15276437 | 0.76 | SLC5A2 (0.45) | SLC5A2SLC5A1MAPTCDALMNA | |
| SCHEMBL19954920 | 0.76 | SLC5A2 (0.45) | SLC5A2SLC5A1MAPTCDALMNA | |
| SCHEMBL24983718 | 0.76 | CDA (0.48) | MAPTCDALMNASMN1; SMN2THRB | |
| SCHEMBL20013397 | 0.72 | MAPT (0.38) | MAPTCDA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3449925-B1 | URIDINE NUCLEOSIDE DERIVATIVES, COMPOSITIONS AND METHODS OF USE | UNIV TUFTS (US) | 2021-08-04 | — | — | EP | disclosed |