Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CDA | P32320 | 1/20 | 0.38 |
| ▸ | ADK | P55263 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GAPDH | P04406 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20013967 | 0.89 | DNPH1 (0.43) | — | |
| SCHEMBL21665429 | 0.78 | MAPT (0.44) | MAPTCDAADKSLC29A1 | |
| SCHEMBL20013408 | 0.78 | MAPT (0.44) | MAPTCDAADKSLC29A1 | |
| SCHEMBL24983718 | 0.76 | CDA (0.48) | MAPTCDASLC29A1 | |
| SCHEMBL23719101 | 0.72 | SLC5A2 (0.46) | MAPTCDA | |
| SCHEMBL20013790 | 0.69 | P2RY6 (0.51) | — | |
| SCHEMBL21665273 | 0.69 | P2RY6 (0.51) | — | |
| SCHEMBL20013789 | 0.69 | DNPH1 (0.44) | — | |
| SCHEMBL22933055 | 0.69 | SMN1; SMN2 (0.41) | MAPTCDAHTR1D | |
| SCHEMBL20013543 | 0.67 | P2RY6 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018058148-A1 | URIDINE NUCLEOSIDE DERIVATIVES, COMPOSITIONS AND METHODS OF USE | TUFTS UNIVERSITY (US) | 2018-03-29 | — | — | WO | disclosed |