Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 8/20 | 0.60 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23719736 | 0.81 | GRM2 (0.55) | GRM2 | |
| SCHEMBL12629355 | 0.81 | GRM2 (0.67) | GRM2DRD2DRD4DRD3 | |
| SCHEMBL14197759 | 0.81 | GRM2 (0.67) | GRM2DRD2DRD4DRD3 | |
| SCHEMBL5328099 | 0.77 | GRM2 (0.51) | GRM2 | |
| SCHEMBL4892766 | 0.76 | GRM2 (0.78) | GRM2DRD2DRD4DRD3 | |
| SCHEMBL4892780 | 0.76 | GRM2 (0.78) | GRM2DRD2DRD4DRD3 | |
| SCHEMBL4892776 | 0.76 | GRM2 (0.78) | GRM2DRD2DRD4DRD3 | |
| SCHEMBL23719405 | 0.75 | GRM2 (1.00) | GRM2DRD2DRD4 | |
| SCHEMBL23719406 | 0.73 | GRM2 (1.00) | GRM2DRD2DRD4 | |
| SCHEMBL5326163 | 0.72 | GRM2 (0.47) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155196-A1 | MODULATORS OF METABOTROPIC GLUTAMATE RECEPTOR 2 | THE GENERAL HOSPITAL CORPORATION (US) | 2021-08-05 | — | — | WO | disclosed |