Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5322682 | 0.84 | GRM2 (0.56) | GRM2 | |
| SCHEMBL5328099 | 0.83 | GRM2 (0.51) | GRM2 | |
| SCHEMBL23719736 | 0.78 | GRM2 (0.55) | GRM2 | |
| SCHEMBL5323729 | 0.76 | GRM2 (0.49) | GRM2 | |
| SCHEMBL5328515 | 0.74 | GRM2 (0.59) | GRM2 | |
| SCHEMBL5327948 | 0.74 | GRM2 (0.47) | GRM2 | |
| SCHEMBL23719604 | 0.72 | GRM2 (0.60) | GRM2 | |
| SCHEMBL23719441 | 0.70 | GRM2 (0.55) | GRM2 | |
| SCHEMBL23719511 | 0.70 | GRM2 (0.63) | GRM2 | |
| SCHEMBL23719509 | 0.70 | GRM2 (0.63) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007135529-A2 | AZABENZIMIDAZOLYL COMPOUNDS AS MGLUR2 POTENTIATORS | PFIZER PRODUCTS INC. (US) | 2007-11-29 | — | — | WO | disclosed |