Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | GAA | P10253 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | XBP1 | P17861 | 1/20 | 0.51 |
| ▸ | IDH2 | P48735 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2288364 | 0.90 | MAPT (0.64) | L3MBTL1MAPTGAAALDH1A1NPSR1 | |
| SCHEMBL8397788 | 0.85 | HDAC8 (0.51) | L3MBTL1MAPTGAAALDH1A1NPSR1 | |
| SCHEMBL6728267 | 0.84 | MEN1 (0.63) | L3MBTL1MAPTGAAALDH1A1NPSR1 | |
| SCHEMBL4100624 | 0.81 | ALDH1A1 (0.55) | L3MBTL1MAPTGAAALDH1A1NPSR1 | |
| SCHEMBL6719698 | 0.80 | MAPT (0.59) | L3MBTL1MAPTGAAALDH1A1NPSR1 | |
| SCHEMBL6719714 | 0.80 | SMN1; SMN2 (0.54) | L3MBTL1MAPTGAAALDH1A1NPSR1 | |
| SCHEMBL6724467 | 0.80 | PTGER3 (0.55) | L3MBTL1MAPTGAAALDH1A1NPSR1 | |
| SCHEMBL7345992 | 0.80 | MAPT (0.59) | L3MBTL1MAPTGAAALDH1A1NPSR1 | |
| SCHEMBL2632866 | 0.80 | MAPT (0.73) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL12412637 | 0.80 | ALDH1A1 (0.76) | L3MBTL1MAPTGAAALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11135222-B2 | Aurora kinase inhibitors | THE REGENTS OF THE UNIVERSIITY OF CALIFORNIA (US) | 2021-10-05 | — | — | US | disclosed |
| EP-3154980-B1 | TETRAHYDROTRIAZOLOPYRIMIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND USES | CHIESI FARM SPA (IT) | 2021-08-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11135222-B2 | Aurora kinase inhibitors | AURKC, AURKA, AURKB | L3MBTL1 1391/4885MAPT 1233/4885GAA 3732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.