SCHEMBL2372026

SCHEMBL2372026

O=S(=O)(N[CH]F)c1cccnc1

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NAPRT Q6XQN6 1/20 0.52
SLC40A1 Q9NP59 5/20 0.50
GLO1 Q04760 1/20 0.50
KMT2A Q03164 2/20 0.48
ALDH1A1 P00352 1/20 0.48
PTGS2 P35354 1/20 0.46
CKS1B P61024 3/20 0.46
SKP2 Q13309 3/20 0.46
KEAP1 Q14145 1/20 0.46
NFE2L2 Q16236 1/20 0.46
SLC1A3 P43003 1/20 0.46
SLC1A2 P43004 1/20 0.46
SLC1A1 P43005 1/20 0.46
CYP3A4 P08684 1/20 0.44
MEN1 O00255 1/20 0.44
MAPT P10636 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2372966 0.81 KMT2A (0.51) NAPRTSLC40A1GLO1KMT2AALDH1A1
SCHEMBL28290634 0.78 CA1 (0.54) KMT2AALDH1A1KEAP1MEN1
SCHEMBL18709576 0.77 NAPRT (0.59) NAPRTSLC40A1GLO1KMT2AALDH1A1
SCHEMBL28538196 0.76 NAPRT (0.57) NAPRTSLC40A1GLO1KMT2AALDH1A1
SCHEMBL21960091 0.76 NAPRT (0.57) NAPRTSLC40A1GLO1KMT2AALDH1A1
SCHEMBL30338836 0.76 NAPRT (0.57) NAPRTSLC40A1GLO1KMT2AALDH1A1
SCHEMBL2371844 0.76 NAPRT (0.57) NAPRTSLC40A1GLO1KMT2AALDH1A1
SCHEMBL2227366 0.76 NAPRT (0.57) NAPRTSLC40A1GLO1KMT2AALDH1A1
SCHEMBL15881331 0.76 NAPRT (0.62) NAPRTSLC40A1GLO1KMT2APTGS2
SCHEMBL27910625 0.76 NAPRT (0.57) NAPRTSLC40A1GLO1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2547204-A2 ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS Bayer Intellectual Property GmbH (DE) 2013-01-23 EP claimed
WO-2011113861-A2 ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2011-09-22 WO claimed
EP-2547204-A2 ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS Bayer Intellectual Property GmbH (DE) 2013-01-23 EP disclosed
WO-2011113861-A2 ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2011-09-22 WO disclosed