SCHEMBL2372966

SCHEMBL2372966

O=S(=O)(N[CH]C(F)(F)F)c1cccnc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.51
NAPRT Q6XQN6 1/20 0.47
SLC40A1 Q9NP59 4/20 0.47
GLO1 Q04760 1/20 0.47
TSHR P16473 1/20 0.45
ALDH1A1 P00352 1/20 0.44
PTGS2 P35354 1/20 0.43
CKS1B P61024 3/20 0.43
SKP2 Q13309 3/20 0.43
KEAP1 Q14145 1/20 0.43
NFE2L2 Q16236 1/20 0.43
SLC1A3 P43003 1/20 0.43
SLC1A2 P43004 1/20 0.43
SLC1A1 P43005 1/20 0.43
CYP3A4 P08684 1/20 0.41
MEN1 O00255 1/20 0.41
MAPT P10636 1/20 0.41
ABCC9 O60706 1/20 0.40
ABCC8 Q09428 1/20 0.40
KCNJ11 Q14654 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2372026 0.81 NAPRT (0.52) KMT2ANAPRTSLC40A1GLO1ALDH1A1
SCHEMBL2442534 0.81 CA1 (0.48) KMT2AALDH1A1KEAP1MEN1
SCHEMBL486015 0.78 KMT2A (0.55) KMT2ANAPRTSLC40A1GLO1TSHR
SCHEMBL12108077 0.75 KMT2A (0.52) KMT2ANAPRTSLC40A1GLO1TSHR
SCHEMBL18709576 0.73 NAPRT (0.59) KMT2ANAPRTSLC40A1GLO1ALDH1A1
SCHEMBL579072 0.73 KMT2A (0.50) KMT2ANAPRTSLC40A1GLO1TSHR
SCHEMBL14626802 0.72 NAPRT (0.49) KMT2ANAPRTSLC40A1TSHRALDH1A1
SCHEMBL578868 0.72 SLC1A3 (0.50) KMT2ANAPRTSLC40A1GLO1TSHR
SCHEMBL578908 0.72 SLC1A3 (0.50) KMT2ANAPRTSLC40A1GLO1TSHR
SCHEMBL578811 0.72 SLC1A3 (0.50) KMT2ANAPRTSLC40A1GLO1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2547204-A2 ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS Bayer Intellectual Property GmbH (DE) 2013-01-23 EP disclosed
WO-2011113861-A2 ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2011-09-22 WO disclosed