Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.57 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.57 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | APEX1 | P27695 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | TNF | P01375 | 1/20 | 0.49 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17774860 | 0.83 | KDM4E (0.58) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL31161439 | 0.82 | ALDH1A1 (0.55) | KDM4EMAPTHIF1AALDH1A1TDP1 | |
| SCHEMBL6651826 | 0.82 | MAPT (0.56) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL15610498 | 0.82 | KDM4E (0.56) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL10528953 | 0.82 | KDM4E (0.60) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL15630970 | 0.82 | KDM4E (0.56) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL8768842 | 0.81 | MAPT (0.54) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL19445617 | 0.78 | KDM4E (0.51) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL29364937 | 0.78 | ALDH1A1 (0.68) | KDM4EMAPTHIF1AALDH1A1TDP1 | |
| SCHEMBL231377 | 0.78 | ALDH1A1 (0.68) | KDM4EMAPTHIF1AALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3875082-A1 | CONJUGATES FOR TREATING DISEASES CAUSED BY PSMA EXPRESSING CELLS | Endocyte, Inc. (US) | 2021-09-08 | — | — | EP | disclosed |
| EP-3858341-A1 | PSMA LIGAND-CONTAINING CONJUGATES FOR THE TREATMENT OF PROSTATE CANCER | Endocyte, Inc. (US) | 2021-08-04 | — | — | EP | disclosed |