Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL944762 | 0.87 | MAP3K5 (0.51) | MAP3K5TNF | |
| SCHEMBL12943387 | 0.79 | MAP3K5 (0.45) | MAP3K5 | |
| SCHEMBL945769 | 0.78 | MAP3K5 (0.53) | MAP3K5TNF | |
| SCHEMBL945392 | 0.77 | MAP3K5 (0.58) | MAP3K5TNF | |
| SCHEMBL14553732 | 0.77 | MAP3K5 (0.50) | MAP3K5TNF | |
| SCHEMBL944055 | 0.77 | MAP3K5 (0.54) | MAP3K5TNF | |
| SCHEMBL944987 | 0.76 | MYLK (0.54) | MAP3K5TNF | |
| SCHEMBL945248 | 0.75 | MAP3K5 (0.52) | MAP3K5TNF | |
| SCHEMBL945153 | 0.75 | MAP3K5 (0.54) | MAP3K5 | |
| SCHEMBL946641 | 0.75 | MAP3K5 (0.59) | MAP3K5TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858824-A1 | APOPTOSIS SIGNAL-REGULATING KINASE INHIBITORS | Gilead Sciences, Inc. (US) | 2021-08-04 | — | — | EP | disclosed |