Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 17/20 | 0.45 |
| ▸ | AKT1 | P31749 | 7/20 | 0.36 |
| ▸ | CBLB | Q13191 | 2/20 | 0.36 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23721207 | 0.82 | MAP3K5 (0.45) | MAP3K5 | |
| SCHEMBL22739302 | 0.77 | MAP3K5 (0.56) | MAP3K5CBLB | |
| SCHEMBL946361 | 0.75 | MAP3K5 (0.53) | MAP3K5 | |
| SCHEMBL944011 | 0.74 | MAP3K5 (0.55) | MAP3K5AKT1 | |
| SCHEMBL12943387 | 0.73 | MAP3K5 (0.45) | MAP3K5PIK3C3 | |
| SCHEMBL23720763 | 0.73 | MAP3K5 (0.37) | MAP3K5AKT1CBLB | |
| SCHEMBL22738977 | 0.70 | MAP3K5 (0.58) | MAP3K5CBLB | |
| SCHEMBL943988 | 0.68 | MAP3K5 (0.69) | MAP3K5CBLB | |
| SCHEMBL945572 | 0.68 | MAP3K5 (0.68) | MAP3K5CBLB | |
| SCHEMBL935947 | 0.67 | MAP3K5 (0.64) | MAP3K5CBLBPIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858824-A1 | APOPTOSIS SIGNAL-REGULATING KINASE INHIBITORS | Gilead Sciences, Inc. (US) | 2021-08-04 | — | — | EP | disclosed |