Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 14/20 | 0.37 |
| ▸ | MYLK | Q15746 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 4/20 | 0.31 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | CBLB | Q13191 | 5/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22738980 | 0.76 | MAP3K5 (0.41) | MAP3K5AKT1TNF | |
| SCHEMBL23721141 | 0.73 | MAP3K5 (0.45) | MAP3K5AKT1CBLB | |
| SCHEMBL22739302 | 0.72 | MAP3K5 (0.56) | MAP3K5CBLB | |
| SCHEMBL23721207 | 0.71 | MAP3K5 (0.45) | MAP3K5MYLK | |
| SCHEMBL22739288 | 0.67 | CBLB (0.34) | CBLB | |
| SCHEMBL22739099 | 0.64 | MAP3K5 (0.43) | MAP3K5AKT1 | |
| SCHEMBL22739036 | 0.63 | MAP3K5 (0.39) | MAP3K5AKT1 | |
| SCHEMBL22738977 | 0.62 | MAP3K5 (0.58) | MAP3K5CBLB | |
| SCHEMBL22738975 | 0.61 | MAP3K5 (0.42) | MAP3K5MYLKAKT1TNFCBLB | |
| SCHEMBL23721029 | 0.61 | MAP3K5 (0.40) | MAP3K5MYLKAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858824-A1 | APOPTOSIS SIGNAL-REGULATING KINASE INHIBITORS | Gilead Sciences, Inc. (US) | 2021-08-04 | — | — | EP | disclosed |