Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 9/20 | 0.39 |
| ▸ | GRIA3 | P42263 | 9/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 9/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.39 |
| ▸ | GRIK5 | Q16478 | 4/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Histidine SCHEMBL28972479 | 0.94 | SLC7A5 (0.40) | SLC7A5CYP3A4CYP1A2GRIA1GRIA3 | |
| Histidine SCHEMBL2761645 | 0.91 | SLC7A5 (0.42) | SLC7A5CYP3A4CYP1A2GRIA1GRIA3 | |
| Histidine SCHEMBL29260571 | 0.91 | SLC7A5 (0.44) | SLC7A5CYP3A4CYP1A2GRIA1GRIA3 | |
| Histidine SCHEMBL3050307 | 0.90 | SLC7A5 (0.49) | SLC7A5CYP3A4CYP1A2GRIA1GRIA3 | |
| Histidine SCHEMBL28093403 | 0.90 | SLC7A5 (0.45) | SLC7A5CYP3A4CYP1A2GRIA1GRIA3 | |
| Histidine SCHEMBL3050310 | 0.90 | SLC7A5 (0.49) | SLC7A5CYP3A4CYP1A2GRIA1GRIA3 | |
| Histidine SCHEMBL3259 | 0.89 | SLC7A5 (0.47) | SLC7A5CYP3A4CYP1A2GRIA1GRIA3 | |
| Histidine SCHEMBL388561 | 0.89 | SLC7A5 (0.47) | SLC7A5CYP3A4CYP1A2GRIA1GRIA3 | |
| Histidine SCHEMBL8316642 | 0.89 | SLC7A5 (0.47) | SLC7A5CYP3A4CYP1A2GRIA1GRIA3 | |
| Histidine SCHEMBL3258 | 0.89 | SLC7A5 (0.47) | SLC7A5CYP3A4CYP1A2GRIA1GRIA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210246019-A1 | PEPTIDE/LIPID-ASSOCIATED NUCLEIC ACIDS (PLANA) FOR NUCLEIC ACID DELIVERY | CHAPMAN UNIVERSITY | 2021-08-12 | — | — | US | disclosed |