Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 5/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 4/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 4/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Histidine SCHEMBL8316642 | 1.00 | SLC7A5 (0.47) | SLC7A5CYP3A4CYP1A2PKMALPI | |
| Histidine SCHEMBL8080341 | 1.00 | SLC7A5 (0.47) | SLC7A5CYP3A4CYP1A2PKMALPI | |
| Histidine SCHEMBL388561 | 1.00 | SLC7A5 (0.47) | SLC7A5CYP3A4CYP1A2PKMALPI | |
| Histidine SCHEMBL18824897 | 1.00 | SLC7A5 (0.47) | SLC7A5CYP3A4CYP1A2PKMALPI | |
| Histidine SCHEMBL388563 | 1.00 | SLC7A5 (0.47) | SLC7A5CYP3A4CYP1A2PKMALPI | |
| Histidine SCHEMBL995910 | 1.00 | SLC7A5 (0.47) | SLC7A5CYP3A4CYP1A2PKMALPI | |
| Histidine SCHEMBL163443 | 1.00 | SLC7A5 (0.47) | SLC7A5CYP3A4CYP1A2PKMALPI | |
| Histidine SCHEMBL3259 | 1.00 | SLC7A5 (0.47) | SLC7A5CYP3A4CYP1A2PKMALPI | |
| Histidine SCHEMBL163442 | 1.00 | SLC7A5 (0.47) | SLC7A5CYP3A4CYP1A2PKMALPI | |
| Histidine SCHEMBL29500208 | 1.00 | SLC7A5 (0.47) | SLC7A5CYP3A4CYP1A2PKMALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 698358 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9974833-B2 | Methods of using compositions comprising variants and fusions of FGF19 polypeptides for modulating bile acid homeostasis in a subject having pregnancy intrahepatic cholestasis | NGM BIOPHARMACEUTICALS, INC. (US) | 2018-05-22 | — | — | US | claimed |
| US-9976076-B2 | Photochromic articles containing a polyoxometalate and methods of making same | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-05-22 | — | — | US | claimed |
| US-9974851-B2 | Human rotavirus vaccine strains and diagnostics | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2018-05-22 | — | — | US | claimed |
| US-9976074-B2 | Self-suspending proppant particulates using canola protein-based hydrogel | HALLIBURTON ENERGY SERVICES, INC. (US) | 2018-05-22 | — | — | US | claimed |
| US-9976184-B2 | Mutations in pancreatic neoplasms | THE JOHNS HOPKINS UNIVERSITY (US) | 2018-05-22 | — | — | US | claimed |
| US-9976077-B2 | Photochromic articles containing polyoxometalate derivatives and methods of making same | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-05-22 | — | — | US | claimed |
| US-9976126-B2 | Modified glycine oxidase | AJINOMOTO CO., INC. (JP) | 2018-05-22 | — | — | US | claimed |
| US-20180136227-A1 | Treatment and Diagnosis of Hereditary Xerocytosis | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-05-17 | — | — | US | claimed |
| US-20180135086-A1 | MICROORGANISM PRODUCING O-ACETYL-HOMOSERINE, AND METHOD FOR PRODUCING O-ACETYL-HOMOSERINE BY USING SAME | CJ CHEILJEDANG CORPORATION (KR) | 2018-05-17 | — | — | US | claimed |
| US-20180134988-A1 | PROCESS FOR REMOVING METAL FROM A METAL-CONTAINING GLYCERIDE OIL COMPRISING A BASIC QUATERNARY AMMONIUM SALT TREATMENT | EVONIK DEGUSSA GMBH (DE) | 2018-05-17 | — | — | US | claimed |
| US-3992524-A | CULTURING STREPTOMYCES ATROFACIENS, MACROMOLECULAR PEPTIDES | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JA) | 1976-11-16 | — | — | US | claimed |
| US-3991107-A | Haloamine transfer | NATIONAL PATENT DEVELOPMENT CORPORATION (US) | 1976-11-09 | — | — | US | claimed |
| US-3988307-A | ATTACHING AN ALPHA,BETA-UNSATURATED AMINO ACID TO A SOLID SUPPORT; ACIDIC AQUEOUS RELEASE AGENT | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) | 1976-10-26 | — | — | US | claimed |
| US-3973574-A | Waving and straightening hair by producing metal chelates in the keratin of the hair | Umezawa, Fumio (JA) | 1976-08-10 | — | — | US | claimed |
| US-3971737-A | [2-Methyl-Ala6 ]LRH | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-07-27 | — | — | US | claimed |
| US-3963691-A | POLYPEPTIDES, PEPTIZATION | MERCK & CO., INC. (US) | 1976-06-15 | — | — | US | claimed |
| US-3959248-A | TRIPEPTIDES; ANTIDEPRESSANTS | MERCK & CO., INC. (US) | 1976-05-25 | — | — | US | claimed |
| US-3953416-A | Synthetic decapeptide having the activity of the luteinizing hormone releasing hormone and method for manufacturing the same | FOLKERS KARL | 1976-04-27 | — | — | US | claimed |
| US-3950513-A | NONTOXIC AMINO ACID | NOVO TERAPEUTISK LABORATORIUM A/S (DK) | 1976-04-13 | — | — | US | claimed |
| US-3943038-A | Method for producing amino acids by culturing hydrogen-oxidizing bacteria | AJINOMOTO CO., INC. (JA) | 1976-03-09 | — | — | US | claimed |