Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 19/20 | 0.56 |
| ▸ | HTR2A | P28223 | 14/20 | 0.56 |
| ▸ | HTR1A | P08908 | 11/20 | 0.56 |
| ▸ | DRD3 | P35462 | 3/20 | 0.49 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19019006 | 0.87 | DRD2 (0.55) | DRD2HTR2AHTR1ADRD3DRD4 | |
| SCHEMBL7835425 | 0.80 | DRD2 (0.57) | DRD2HTR2AHTR1ADRD3DRD4 | |
| SCHEMBL7850186 | 0.80 | DRD2 (0.57) | DRD2HTR2AHTR1ADRD3DRD4 | |
| SCHEMBL1042913 | 0.80 | DRD2 (0.57) | DRD2HTR2AHTR1ADRD3DRD4 | |
| SCHEMBL19018993 | 0.78 | DRD2 (0.54) | DRD2HTR2AHTR1ADRD3DRD4 | |
| SCHEMBL12045242 | 0.77 | DRD2 (0.62) | DRD2HTR2AHTR1ADRD3DRD4 | |
| SCHEMBL19018842 | 0.77 | DRD2 (0.54) | DRD2HTR2AHTR1ADRD3DRD4 | |
| SCHEMBL3260646 | 0.77 | DRD2 (0.80) | DRD2HTR2AHTR1ADRD3DRD4 | |
| SCHEMBL22417544 | 0.76 | DRD2 (0.49) | DRD2HTR2AHTR1ADRD3DRD4 | |
| SCHEMBL22417545 | 0.76 | DRD2 (0.54) | DRD2HTR2AHTR1ADRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2445343-B1 | PRODRUGS OF NH-ACIDIC COMPOUNDS | ALKERMES PHARMA IRELAND LTD (IE) | 2021-08-04 | — | — | EP | disclosed |