Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | PLEC | Q15149 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | ALPG | P10696 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 9/20 | 0.44 |
| ▸ | CA1 | P00915 | 7/20 | 0.44 |
| ▸ | CA2 | P00918 | 7/20 | 0.44 |
| ▸ | CA12 | O43570 | 5/20 | 0.44 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | GJA1 | P17302 | 1/20 | 0.41 |
| ▸ | GJB2 | P29033 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20600863 | 0.99 | USP2 (0.52) | USP2MEN1POLBKMT2AATM | |
| SCHEMBL20600864 | 0.87 | USP2 (0.53) | USP2MEN1POLBKMT2AATM | |
| SCHEMBL30388412 | 0.87 | USP2 (0.53) | USP2MEN1POLBKMT2AATM | |
| SCHEMBL20600870 | 0.87 | USP2 (0.53) | USP2MEN1POLBKMT2AATM | |
| SCHEMBL20600846 | 0.87 | USP2 (0.55) | USP2MEN1POLBKMT2AATM | |
| SCHEMBL20600850 | 0.87 | USP2 (0.55) | USP2MEN1POLBKMT2AATM | |
| Bromide SCHEMBL29487272 | 0.84 | USP2 (0.51) | USP2MEN1POLBKMT2AATM | |
| Bromide SCHEMBL25262541 | 0.84 | USP2 (0.51) | USP2MEN1POLBKMT2AATM | |
| SCHEMBL16579859 | 0.80 | USP2 (0.56) | USP2MEN1POLBKMT2AATM | |
| SCHEMBL3873447 | 0.80 | USP2 (0.56) | USP2MEN1POLBKMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210246144-A1 | A SET OF MITOCHONDRIA-TARGETED COMPOUNDS | MITOTECH S.A. (LU) | 2021-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210246144-A1 | A SET OF MITOCHONDRIA-TARGETED COMPOUNDS | COQ8A, TIMM50, TIMM10 | USP2 4585/4885MEN1 2615/4885POLB 1885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.