SCHEMBL23723484

SCHEMBL23723484

N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OOC(=O)[C@@H](N)Cc1c[nH]c2ccccc12

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.76
KDM4E B2RXH2 2/20 0.76
MEN1 O00255 2/20 0.76
LMNA P02545 2/20 0.76
KMT2A Q03164 2/20 0.76
MPO P05164 1/20 0.76
TSHR P16473 1/20 0.76
BLM P54132 1/20 0.76
PMP22 Q01453 1/20 0.76
HIF1A Q16665 1/20 0.76
TACR1 P25103 2/20 0.67
HTR2A P28223 2/20 0.60
ADRB1 P08588 1/20 0.60
HTR1A P08908 1/20 0.60
ADRA2A P08913 1/20 0.60
SLC6A2 P23975 1/20 0.60
HTR1D P28221 1/20 0.60
HTR1B P28222 1/20 0.60
HTR2C P28335 1/20 0.60
HTR1E P28566 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29472033 1.00 MAPT (0.76) MAPTKDM4EMEN1LMNAKMT2A
SCHEMBL289044 0.93 MAPT (0.74) MAPTKDM4EMEN1LMNAKMT2A
SCHEMBL475351 0.93 MAPT (0.74) MAPTKDM4EMEN1LMNAKMT2A
SCHEMBL18870211 0.92 MAPT (0.68) MAPTKDM4EMEN1LMNAKMT2A
SCHEMBL1981757 0.92 MAPT (0.68) MAPTKDM4EMEN1LMNAKMT2A
SCHEMBL28780405 0.91 MAPT (0.72) MAPTKDM4EMEN1LMNAKMT2A
SCHEMBL1278452 0.91 MAPT (0.72) MAPTKDM4EMEN1LMNAKMT2A
SCHEMBL626831 0.91 MAPT (0.72) MAPTKDM4EMEN1LMNAKMT2A
Tryptophan Methyl Ester SCHEMBL1195735 0.90 MEN1 (0.70) MAPTKDM4EMEN1LMNAKMT2A
SCHEMBL21059260 0.90 MAPT (0.70) MAPTKDM4EMEN1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230096635-A1 CROSS-LINKED POLYMERIC MATERIALS, METHODS OF THEIR PREPARATION AND USES THEREOF THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2023-03-30 US disclosed
EP-4100459-A1 CROSS-LINKED POLYMERIC MATERIALS, METHODS OF THEIR PREPARATION AND USES THEREOF The University of British Columbia (CA) 2022-12-14 EP disclosed
WO-2021155461-A1 CROSS-LINKED POLYMERIC MATERIALS, METHODS OF THEIR PREPARATION AND USES THEREOF THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2021-08-12 WO disclosed
CN-1826170-B Methods for fabrication, uses and compositions of small spherical particles prepared by controlled phase separation BAXTER INT 2010-12-08 CN disclosed
CN-1826170-A Methods for fabrication, uses and compositions of small spherical particles of hgh prepared by controlled phase separation BAXTER INT (US) 2006-08-30 CN disclosed