Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | MPO | P05164 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.74 |
| ▸ | BLM | P54132 | 1/20 | 0.74 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.74 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.74 |
| ▸ | TACR1 | P25103 | 2/20 | 0.66 |
| ▸ | HTR2A | P28223 | 2/20 | 0.59 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.59 |
| ▸ | HTR1A | P08908 | 1/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | HTR1D | P28221 | 1/20 | 0.59 |
| ▸ | HTR1B | P28222 | 1/20 | 0.59 |
| ▸ | HTR2C | P28335 | 1/20 | 0.59 |
| ▸ | HTR1E | P28566 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL475351 | 1.00 | MAPT (0.74) | MAPTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL27645874 | 0.95 | MAPT (0.67) | MAPTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL4261073 | 0.95 | MAPT (0.67) | MAPTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL21059260 | 0.94 | MAPT (0.70) | MAPTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL120931 | 0.93 | KDM4E (0.69) | MAPTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL8406415 | 0.93 | MAPT (0.65) | MAPTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL5065255 | 0.93 | KDM4E (0.65) | MAPTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL17503190 | 0.93 | MAPT (0.72) | MAPTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL1640627 | 0.93 | MAPT (0.68) | MAPTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL626831 | 0.93 | MAPT (0.72) | MAPTKDM4EMEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1637185-B1 | Controlled-release formulations containing tryptophan and/or 5-hydroxytryptophan | AMBROS PHARMA S R L (IT) | 2008-08-20 | — | — | EP | claimed |
| US-5892112-A | ACYLATION OF AMINO ACIDS WITH ANHYDRIDES OR CARBOXY GROUPS, AMIDATION WITH AMINE AND CONVERSION OF ACID OR ESTER TO HYDROXAMIC ACID AND HYDROLYSIS | GLYCOMED INCORPORATED (US) | 1999-04-06 | — | — | US | claimed |
| CN-115304661-B | Cyclic peptide compound and application thereof | 西南民族大学 | 2024-03-15 | — | — | CN | disclosed |
| CN-107304191-B | Indolylamine 2,3-dioxygenase inhibitor and preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-111491923-B | N- (2-cyclohexylethyl) carboxamide derivatives, preparation and pharmaceutical use thereof | 上海海雁医药科技有限公司 | 2023-06-16 | — | — | CN | disclosed |
| WO-2023088591-A1 | BACTERIAL STRAIN AND THE USE THEREOF | PROBITAT OY (FI) | 2023-05-25 | — | — | WO | disclosed |
| CN-112384502-B | Cycloalkyl-substituted amide derivatives, preparation method and medical application thereof | 上海海雁医药科技有限公司 | 2022-11-08 | — | — | CN | disclosed |
| CN-106883193-B | Indoleamine 2,3-dioxygenase inhibitor as well as preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2021-10-15 | — | — | CN | disclosed |
| CN-108424944-B | Optimized production method and culture medium of candicidin | 华东理工大学 | 2021-07-27 | — | — | CN | disclosed |
| CN-112384502-A | Cycloalkyl-substituted amide derivatives, preparation method and medical application thereof | 上海海雁医药科技有限公司 | 2021-02-19 | — | — | CN | disclosed |
| CN-110105275-B | Amide derivatives, preparation method and medical application thereof | 上海海雁医药科技有限公司 | 2020-12-29 | — | — | CN | disclosed |
| CN-101969984-A | Haemostasis- modulating compositions and uses therefor | UNIV QUEENSLAND | 2011-02-09 | — | — | CN | disclosed |
| WO-2011000753-A1 | METHOD FOR NORMALIZATION IN METABOLOMICS ANALYSIS METHODS WITH ENDOGENOUS REFERENCE METABOLITES | BIOCRATES LIFE SCIENCES AG (AT) | 2011-01-06 | — | — | WO | disclosed |
| WO-2010128054-A1 | METHOD OF DIAGNOSING ASPHYXIA | BIOCRATES LIFE SCIENCES AG (AT) | 2010-11-11 | — | — | WO | disclosed |
| WO-2010075287-A2 | COMPOUNDS AND METHODS FOR THE TREATMENT OF PAIN AND OTHER DISEASES | AQUILUS PHARMACEUTICALS, INC (US) | 2010-07-01 | — | — | WO | disclosed |
| CN-101541379-A | Methods for modulating cell survival | INST MEDICAL W & E HALL (AU) | 2009-09-23 | — | — | CN | disclosed |
| CN-1938042-A | Methods for mitigating oxidative damage | CORNELL RES FOUNDATION INC (US) | 2007-03-28 | — | — | CN | disclosed |
| US-5460725-A | Crosslinked copolymer of monovinyl aromatic monomer, monovinyl aliphatic monomer, and polyvinyl aromatic monomer; chromatography | THE DOW CHEMICAL COMPANY (US) | 1995-10-24 | — | — | US | disclosed |
| US-5185157-A | With solid or liquid carrier, free of zinc, magnesium and calcium salts | TYSON & ASSOCIATES, INC. | 1993-02-09 | — | — | US | disclosed |
| US-4778808-A | CONCENTRATING CULTURE BROTH WHILE CONTROLLING PH AND TEMPERATURE STABILITY | AJINOMOTO CO., INC. (JP) | 1988-10-18 | — | — | US | disclosed |