Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 4/20 | 0.60 |
| ▸ | HRH2 | P25021 | 2/20 | 0.60 |
| ▸ | HTR2A | P28223 | 2/20 | 0.60 |
| ▸ | DRD3 | P35462 | 2/20 | 0.60 |
| ▸ | HTR2B | P41595 | 2/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 2/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.60 |
| ▸ | TEK | Q02763 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3243434 | 1.00 | HRH1 (0.60) | HRH1HRH2HTR2ADRD3HTR2B | |
| Hydrochloric Acid SCHEMBL3818204 | 0.99 | HRH1 (0.60) | HRH1HRH2HTR2ADRD3HTR2B | |
| Hydrochloric Acid SCHEMBL5682715 | 0.99 | HRH1 (0.60) | HRH1HRH2HTR2ADRD3HTR2B | |
| SCHEMBL5272706 | 0.92 | HRH1 (0.50) | HRH1HRH2HTR2ADRD3HTR2B | |
| SCHEMBL5182116 | 0.90 | HRH1 (0.48) | HRH1HRH2HTR2ADRD3HTR2B | |
| SCHEMBL6631216 | 0.88 | HRH1 (0.58) | HRH1HRH2HTR2ADRD3HTR2B | |
| SCHEMBL4431100 | 0.86 | SLC6A9 (0.45) | HRH1HRH2HTR2ADRD3HTR2B | |
| Hydrochloric Acid SCHEMBL21462452 | 0.85 | HRH1 (0.45) | HRH1HRH2HTR2ADRD3HTR2B | |
| Hydrochloric Acid SCHEMBL5686146 | 0.85 | HRH1 (0.45) | HRH1HRH2HTR2ADRD3HTR2B | |
| Hydrochloric Acid SCHEMBL6951585 | 0.85 | HRH1 (0.45) | HRH1HRH2HTR2ADRD3HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4099977-A1 | A SINGLE LAYER CHEWABLE TABLET COMPRISING CETIRIZINE | Johnson & Johnson Consumer Inc. (US) | 2022-12-14 | — | — | EP | disclosed |
| WO-2021156698-A1 | A SINGLE LAYER CHEWABLE TABLET COMPRISING CETIRIZINE | JOHNSON & JOHNSON CONSUMER INC. (US) | 2021-08-12 | — | — | WO | disclosed |