Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8301383 | 1.00 | MEN1 (0.57) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL3882849 | 0.98 | MEN1 (0.55) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL9093407 | 0.92 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL11490414 | 0.87 | ALDH1A1 (0.55) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL372350 | 0.87 | ALDH1A1 (0.55) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL28443081 | 0.85 | MAPT (0.50) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL28450924 | 0.85 | MAPT (0.50) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL28443083 | 0.85 | MAPT (0.50) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL20066231 | 0.85 | CHRM1 (0.53) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL3273470 | 0.85 | ALDH1A1 (0.62) | MEN1KMT2AALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011119704-A1 | TRPV4 ANTAGONISTS | GLAXOSMITHKLINE LLC (US) | 2011-09-29 | — | — | WO | disclosed |
| EP-0686625-B1 | ANTHRANILIC ACID DERIVATIVE | EISAI CO LTD (JP) | 1999-05-26 | — | — | EP | disclosed |
| US-5716993-A | PHOSPHODIESTERASE ENZYME INHIBITOR FOR TREATING CARDIOVASCULAR DISORDER, ANGINA PECTORIS, HYPERTENSION, ASTHMA | EISAI CO., LTD. (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0686625-A1 | ANTHRANILIC ACID DERIVATIVE | Eisai Co., Ltd. (JP) | 1995-12-13 | — | — | EP | disclosed |