Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.75 |
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MARS2 | Q96GW9 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2343711 | 0.87 | NPC1 (0.56) | NPC1MEN1KMT2AALDH1A1CNR1 | |
| SCHEMBL28797399 | 0.84 | NPC1 (0.71) | NPC1MEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL17087086 | 0.83 | NPC1 (0.69) | NPC1MEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL23727617 | 0.83 | NPC1 (0.52) | NPC1MEN1KMT2AALDH1A1CNR1 | |
| SCHEMBL15229375 | 0.82 | MEN1 (0.56) | NPC1MEN1KMT2AALDH1A1BCAT2 | |
| SCHEMBL29206351 | 0.82 | KMT2A (0.73) | NPC1MEN1KMT2AALDH1A1CNR1 | |
| SCHEMBL4872704 | 0.81 | NPC1 (0.61) | NPC1MEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL6693064 | 0.80 | NPC1 (0.69) | NPC1MEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL2294626 | 0.80 | NPC1 (0.69) | NPC1MEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL2295601 | 0.80 | NPC1 (0.69) | NPC1MEN1KMT2AALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313157-A1 | ENZYME-TRIGGERED SELF-REACTING LINKER HAVING IMPROVED PHYSICOCHEMICAL AND PHARMACOLOGICAL PROPERTIES | Mablink Bioscience (FR) | 2024-02-07 | — | — | EP | disclosed |
| WO-2023170247-A1 | ANTIBODY-DRUG CONJUGATES AND THEIR USES | MABLINK BIOSCIENCE (FR) | 2023-09-14 | — | — | WO | disclosed |
| US-20230133132-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. | 2023-05-04 | — | — | US | disclosed |
| EP-4100393-A1 | NAMPT MODULATORS | Cytokinetics, Inc. (US) | 2022-12-14 | — | — | EP | disclosed |
| WO-2021159015-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. (US) | 2021-08-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230133132-A1 | NAMPT MODULATORS | NAMPT, MC4R, SIRT1 | NPC1 463/4885MEN1 484/4885KMT2A 1669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.