Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRAS | P01112 | 8/20 | 0.39 |
| ▸ | ESR1 | P03372 | 8/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.39 |
| ▸ | TOP1 | P11387 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | ZAP70 | P43403 | 2/20 | 0.33 |
| ▸ | SYK | P43405 | 2/20 | 0.33 |
| ▸ | HASPIN | Q8TF76 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23728754 | 0.86 | P2RX3 (0.42) | P2RX3ZAP70SYK | |
| Hydrochloric Acid SCHEMBL23728767 | 0.85 | P2RX3 (0.41) | KDM4EPOLBMAPTHIF1AP2RX3 | |
| SCHEMBL23728917 | 0.82 | P2RX3 (0.34) | HRASESR1ESR2TOP1KDM4E | |
| SCHEMBL23728948 | 0.80 | CA1 (0.39) | MAPTHDAC1HDAC2HDAC8CA1 | |
| Hydrochloric Acid SCHEMBL23728962 | 0.79 | CA1 (0.38) | KDM4EPOLBMAPTHIF1AHDAC1 | |
| SCHEMBL23728909 | 0.77 | RPS6KA3 (0.31) | HDAC1HDAC2HDAC8 | |
| SCHEMBL23728782 | 0.76 | HDAC1 (0.33) | HRASESR1ESR2TOP1HDAC1 | |
| SCHEMBL23744936 | 0.73 | HDAC1 (0.56) | HRASESR1ESR2TOP1KDM4E | |
| SCHEMBL23728785 | 0.72 | STK17B (0.40) | P2RX3 | |
| SCHEMBL23728857 | 0.71 | STK17B (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4384506-A1 | PROCESS FOR POLYAMIDE SYNTHESIS | Design Therapeutics, Inc. (US) | 2024-06-19 | — | — | EP | disclosed |
| WO-2023014793-A1 | PROCESS FOR POLYAMIDE SYNTHESIS | Design Therapeutics, Inc. (US) | 2023-02-09 | — | — | WO | disclosed |
| EP-4100404-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | Design Therapeutics, Inc. (US) | 2022-12-14 | — | — | EP | disclosed |
| WO-2021158707-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | Design Therapeutics, Inc. (US) | 2021-08-12 | — | — | WO | disclosed |