⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23728940 | 0.92 | P2RY12 (0.31) | — | |
| SCHEMBL23728911 | 0.90 | MEN1 (0.33) | — | |
| SCHEMBL23728949 | 0.90 | MEN1 (0.33) | — | |
| SCHEMBL23728922 | 0.88 | HDAC1 (0.32) | — | |
| SCHEMBL23728864 | 0.85 | TOP1 (0.33) | — | |
| SCHEMBL23728900 | 0.85 | MC4R (0.35) | — | |
| SCHEMBL23728958 | 0.83 | KDM4E (0.33) | — | |
| SCHEMBL23728934 | 0.83 | KDM4E (0.33) | — | |
| SCHEMBL23728952 | 0.82 | P2RX3 (0.35) | — | |
| SCHEMBL23728901 | 0.82 | TOP1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4100404-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | Design Therapeutics, Inc. (US) | 2022-12-14 | — | — | EP | disclosed |
| WO-2021158707-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | Design Therapeutics, Inc. (US) | 2021-08-12 | — | — | WO | disclosed |