Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 4/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PI4KA | P42356 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | CCR1 | P32246 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL550080 | 0.92 | TLR4 (0.47) | TLR4TLR2HTR1AHTR7CYP2A6 | |
| SCHEMBL28432843 | 0.86 | GRM5 (0.43) | TLR4TLR2HTR1AHTR7CYP2A6 | |
| SCHEMBL17127133 | 0.82 | KDM4E (0.43) | TLR4TLR2CYP2A6CYP1A2CYP2D6 | |
| SCHEMBL10022089 | 0.81 | TLR4 (0.55) | TLR4TLR2HTR1AHTR7CYP2A6 | |
| SCHEMBL550707 | 0.81 | KDM4E (0.48) | CYP2A6CYP1A2CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL10022088 | 0.80 | TLR4 (0.50) | TLR4TLR2HTR1AHTR7CYP2A6 | |
| SCHEMBL30772294 | 0.79 | KDM4E (0.50) | CYP2A6CYP1A2CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL99284 | 0.79 | KDM4E (0.50) | CYP2A6CYP1A2CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL16615368 | 0.78 | TRPV1 (0.47) | HTR1AHTR7CYP2A6GRM5CYP1A2 | |
| SCHEMBL30903581 | 0.78 | TLR4 (0.57) | TLR4TLR2HTR1AHTR7CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858945-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | Universal Display Corporation (US) | 2021-08-04 | — | — | EP | disclosed |