SCHEMBL99284

SCHEMBL99284

C=Cc1ccc(-c2ccccn2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.50
LMNA P02545 3/20 0.50
CYP1A2 P05177 2/20 0.50
CCR1 P32246 2/20 0.50
CCR5 P51681 2/20 0.50
CCR8 P51685 2/20 0.50
POLB P06746 1/20 0.50
METAP1 P53582 1/20 0.50
BLM P54132 1/20 0.50
HIF1A Q16665 1/20 0.50
DOHH Q9BU89 1/20 0.50
P4HTM Q9NXG6 1/20 0.50
CYP2D6 P10635 1/20 0.46
CYP19A1 P11511 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
CA12 O43570 2/20 0.46
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
CA9 Q16790 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30772294 1.00 KDM4E (0.50) KDM4ELMNACYP1A2CCR1CCR5
SCHEMBL550707 0.98 KDM4E (0.48) KDM4ELMNACYP1A2CCR1CCR5
SCHEMBL5572413 0.98 KDM4E (0.48) KDM4ELMNACYP1A2CCR1CCR5
SCHEMBL2887508 0.94 CYP2A6 (0.46) KDM4ELMNACYP1A2CCR1CCR5
Pyridine SCHEMBL28163770 0.93 CYP2A6 (0.49) KDM4ELMNACYP1A2CCR1CCR5
SCHEMBL14270342 0.90 CA12 (0.50) KDM4ELMNACYP1A2CCR1CCR5
SCHEMBL17127133 0.89 KDM4E (0.43) KDM4ELMNACYP1A2CCR1CCR5
SCHEMBL7963566 0.88 KDM4E (0.60) KDM4ELMNACYP1A2CCR1CCR5
SCHEMBL550080 0.86 TLR4 (0.47) KDM4ELMNACYP1A2CCR1CCR5
SCHEMBL550438 0.85 KDM4E (0.43) KDM4ELMNACYP1A2CCR1CCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104356053-B Preparation method of 2-(3-halogen phenyl) pyridine derivative 天津大学 2017-01-18 CN claimed
CN-104170110-B organic electroluminescent element 国立大学法人山形大学 2016-11-02 CN claimed
US-9425411-B2 Organic electroluminescent element NATIONAL UNIVERSITY CORPORATION YAMAGATA UNIVERSITY (JP) 2016-08-23 US claimed
US-20160020406-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NATIONAL UNIVERSITY CORPORATION YAMAGATA UNIVERSITY (JP) 2016-01-21 US claimed
CN-104356053-A Preparation method of 2-(3-halogen phenyl) pyridine derivative UNIV TIANJIN 2015-02-18 CN claimed
CN-104170110-A Organic electroluminescent element NAT UNIV CORP YAMAGATA UNIV 2014-11-26 CN claimed
WO-2004031321-A1 OXYGEN SENSING COMPOUNDS, METHODS FOR PRODUCTION THEREOF AND THEIR USES NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2004-04-15 WO claimed
EP-4561973-A1 PROCESS FOR THE PRODUCTION OF METHANOL AND HYDROGEN FROM METHANE USING A LIQUID REACTANT TotalEnergies OneTech (FR) 2025-06-04 EP disclosed
US-20250171388-A1 Process For the Production of Methanol and Hydrogen from Methane Using a Liquid Reactant SULZER MANAGEMENT AG (CH) 2025-05-29 US disclosed
WO-2024023020-A1 PROCESS FOR THE PRODUCTION OF METHANOL AND HYDROGEN FROM METHANE USING A LIQUID REACTANT TOTALENERGIES ONETECH (FR) 2024-02-01 WO disclosed
CN-117430549-A Method for preparing isonicotinic acid compound by taking carbon dioxide as carboxyl source 南开大学 2024-01-23 CN disclosed
US-20230322691-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT CANON KABUSHIKI KAISHA (JP) 2023-10-12 US disclosed
US-11031562-B2 Metal complexes MERCK PATENT GMBH (DE) 2021-06-08 US disclosed
EP-1426399-A1 HIGH−MOLECULAR COMPOUNDS AND ORGANIC LUMINESCENT DEVICES Canon Kabushiki Kaisha (JP) 2004-06-09 EP disclosed
WO-2004031321-A1 OXYGEN SENSING COMPOUNDS, METHODS FOR PRODUCTION THEREOF AND THEIR USES NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2004-04-15 WO disclosed
US-6660821-B2 Vinyl-phenyl pyridine monomers and polymers prepared thereform KWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2003-12-09 US disclosed
US-20030186080-A1 High-molecular compounds and organic luminescent devices CANON KABUSHIKI KAISHA (JP) 2003-10-02 US disclosed
US-20030176709-A1 Vinyl-phenyl pyridine monomers and polymers prepared thereform KWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY 2003-09-18 US disclosed
US-6545159-B2 Suzuki coupling reaction of vinyl-phenylboronic acid and 2-bromopyridine in presence of alkali metallic base and tetrakis/triphenylphosphine/palladium to form styrenepyridine monomer KWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2003-04-08 US disclosed
US-20020198346-A1 Vinyl-phenyl pyridine monomers and polymers prepared thereform KWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY 2002-12-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230322691-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT CCNT1, CCNE2, SCO2 KDM4E 3380/4885LMNA 701/4885CYP1A2 182/4885
US-11031562-B2 Metal complexes AP1M1, SOD1, AP3M1 KDM4E 3482/4885LMNA 4426/4885CYP1A2 3622/4885
US-20020198346-A1 Vinyl-phenyl pyridine monomers and polymers prepared thereform VAT1, PBRM1, THEM6 KDM4E 1455/4885LMNA 4034/4885CYP1A2 318/4885
US-20030176709-A1 Vinyl-phenyl pyridine monomers and polymers prepared thereform VAT1, PBRM1, THEM6 KDM4E 1455/4885LMNA 4034/4885CYP1A2 318/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.