Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25876044 | 0.81 | HRH3 (0.48) | HRH3L3MBTL1KDM4EALDH1A1MEN1 | |
| SCHEMBL16133962 | 0.80 | HRH3 (0.54) | HRH3L3MBTL1KDM4EALDH1A1MEN1 | |
| SCHEMBL19754841 | 0.80 | HRH3 (0.54) | HRH3L3MBTL1KDM4EALDH1A1MEN1 | |
| SCHEMBL26700695 | 0.79 | HRH3 (0.52) | HRH3L3MBTL1KDM4EALDH1A1MEN1 | |
| SCHEMBL10130724 | 0.78 | HRH3 (0.51) | HRH3L3MBTL1KDM4EALDH1A1MEN1 | |
| SCHEMBL13043900 | 0.78 | HRH3 (0.51) | HRH3L3MBTL1KDM4EALDH1A1MEN1 | |
| SCHEMBL18195129 | 0.77 | L3MBTL1 (0.65) | HRH3L3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL4915015 | 0.77 | HRH3 (0.48) | HRH3L3MBTL1KDM4EALDH1A1MEN1 | |
| SCHEMBL19754840 | 0.77 | ATM (0.48) | HRH3L3MBTL1KDM4EALDH1A1MEN1 | |
| SCHEMBL10975755 | 0.77 | HRH3 (0.51) | HRH3L3MBTL1KDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155321-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |