Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 18/20 | 0.80 |
| ▸ | CRBN | Q96SW2 | 18/20 | 0.80 |
| ▸ | STAT3 | P40763 | 1/20 | 0.57 |
| ▸ | GSPT1 | P15170 | 4/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20208207 | 0.91 | DDB1 (0.87) | DDB1CRBNSTAT3GSPT1 | |
| SCHEMBL23915930 | 0.90 | DDB1 (0.85) | DDB1CRBNSTAT3GSPT1 | |
| SCHEMBL23915699 | 0.90 | DDB1 (0.85) | DDB1CRBNSTAT3GSPT1 | |
| SCHEMBL23915252 | 0.90 | DDB1 (0.85) | DDB1CRBNSTAT3GSPT1 | |
| SCHEMBL20208257 | 0.90 | DDB1 (0.85) | DDB1CRBNSTAT3GSPT1 | |
| SCHEMBL20153910 | 0.89 | CRBN (1.00) | DDB1CRBNSTAT3GSPT1 | |
| SCHEMBL23729668 | 0.89 | CRBN (0.75) | DDB1CRBNSTAT3PDK2 | |
| SCHEMBL26614603 | 0.89 | DDB1 (0.63) | DDB1CRBNSTAT3GSPT1PDK2 | |
| Trifluoroacetic Acid SCHEMBL30060912 | 0.88 | DDB1 (0.79) | DDB1CRBNSTAT3GSPT1 | |
| SCHEMBL20208371 | 0.88 | CRBN (0.90) | DDB1CRBNSTAT3GSPT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348452-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2023-11-02 | — | — | US | disclosed |
| US-20230348452-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2023-11-02 | — | — | US | disclosed |
| WO-2021155321-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348452-A1 | COMPOUNDS AND USES THEREOF | VHL, CLN6, BRCA1 | DDB1 576/4885CRBN 163/4885STAT3 3997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.