Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 13/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 13/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 12/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 12/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 11/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 11/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 11/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 10/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 10/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 10/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 10/20 | 0.49 |
| ▸ | MEF2D | Q14814 | 2/20 | 0.47 |
| ▸ | EP300 | Q09472 | 1/20 | 0.47 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.45 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23705614 | 0.86 | SMARCA2 (0.61) | HDAC6HDAC1HDAC4HDAC2HDAC3 | |
| SCHEMBL23705613 | 0.86 | SMARCA2 (0.61) | HDAC6HDAC1HDAC4HDAC2HDAC3 | |
| SCHEMBL21224166 | 0.86 | HDAC6 (0.58) | HDAC6HDAC1HDAC4HDAC2HDAC3 | |
| SCHEMBL21224170 | 0.86 | HDAC6 (0.58) | HDAC6HDAC1HDAC4HDAC2HDAC3 | |
| SCHEMBL23730007 | 0.85 | HDAC1 (0.51) | HDAC6HDAC1HDAC4HDAC2HDAC3 | |
| SCHEMBL23730012 | 0.84 | SMARCA2 (0.46) | HDAC6HDAC1HDAC4HDAC2HDAC3 | |
| SCHEMBL23729740 | 0.82 | SMARCA2 (0.50) | HDAC6HDAC1HDAC4HDAC2HDAC3 | |
| SCHEMBL5472600 | 0.81 | HDAC6 (0.61) | HDAC6HDAC1HDAC4HDAC2HDAC3 | |
| SCHEMBL23730119 | 0.81 | SMARCA2 (0.49) | SMARCA2SMARCA4 | |
| SCHEMBL5366535 | 0.80 | HDAC6 (0.60) | HDAC6HDAC1HDAC4HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155321-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |