Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.57 |
| ▸ | SCD | O00767 | 1/20 | 0.57 |
| ▸ | PARP1 | P09874 | 1/20 | 0.54 |
| ▸ | EP300 | Q09472 | 1/20 | 0.53 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21224170 | 1.00 | HDAC6 (0.58) | HDAC6HDAC1HDAC4HDAC3HDAC7 | |
| SCHEMBL5472600 | 0.90 | HDAC6 (0.61) | HDAC6HDAC1HDAC4HDAC3HDAC7 | |
| SCHEMBL5366535 | 0.89 | HDAC6 (0.60) | HDAC6HDAC1HDAC4HDAC3HDAC7 | |
| SCHEMBL21241916 | 0.88 | SCD (0.58) | HDAC6HDAC1HDAC4HDAC3HDAC7 | |
| SCHEMBL21241784 | 0.88 | SCD (0.58) | HDAC6HDAC1HDAC4HDAC3HDAC7 | |
| SCHEMBL28528489 | 0.88 | HDAC6 (0.58) | HDAC6HDAC1HDAC4HDAC3HDAC7 | |
| SCHEMBL28528487 | 0.87 | HDAC6 (0.56) | HDAC6HDAC1HDAC4HDAC3HDAC7 | |
| SCHEMBL23729256 | 0.86 | HDAC6 (0.49) | HDAC6HDAC1HDAC4HDAC3HDAC7 | |
| SCHEMBL21241915 | 0.86 | HDAC6 (0.57) | HDAC6HDAC1HDAC4HDAC3HDAC7 | |
| SCHEMBL21241793 | 0.86 | HDAC6 (0.57) | HDAC6HDAC1HDAC4HDAC3HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12383560-B2 | Compounds and uses thereof | FOGHORN THERAPEUTICS INC. (US) | 2025-08-12 | — | — | US | disclosed |
| US-20230138480-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2023-05-04 | — | — | US | disclosed |
| US-20230138480-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2023-05-04 | — | — | US | disclosed |
| US-20230138480-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2023-05-04 | — | — | US | disclosed |
| US-11497752-B2 | Compounds and uses thereof | FOGHORN THERAPEUTICS INC. (US) | 2022-11-15 | — | — | US | disclosed |
| US-20210038611-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2021-02-11 | — | — | US | disclosed |
| US-20210038611-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2021-02-11 | — | — | US | disclosed |
| CN-112153984-A | Compound and use thereof | 福宏治疗公司 | 2020-12-29 | — | — | CN | disclosed |
| EP-3746124-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2020-12-09 | — | — | EP | disclosed |
| WO-2019152437-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2019-08-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230138480-A1 | COMPOUNDS AND USES THEREOF | VHL, CLN6, TFEB | HDAC6 86/4885HDAC1 242/4885HDAC4 152/4885 |
| US-12383560-B2 | Compounds and uses thereof | VHL, CLN6, TFEB | HDAC6 86/4885HDAC1 242/4885HDAC4 152/4885 |
| US-11497752-B2 | Compounds and uses thereof | VHL, CLN6, TFEB | HDAC6 86/4885HDAC1 242/4885HDAC4 152/4885 |
| US-20210038611-A1 | COMPOUNDS AND USES THEREOF | VHL, CLN6, TFEB | HDAC6 86/4885HDAC1 242/4885HDAC4 152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.