Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | CNR1 | P21554 | 4/20 | 0.43 |
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CASP2 | P42575 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | GLP1R | P43220 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23729313 | 0.84 | HPGD (0.46) | HPGDCNR1CNR2TSHRSMN1; SMN2 | |
| SCHEMBL23730062 | 0.84 | HPGD (0.46) | HPGDCNR1CNR2TSHRSMN1; SMN2 | |
| SCHEMBL26700881 | 0.83 | HPGD (0.45) | HPGDCNR1CNR2TSHRSMN1; SMN2 | |
| SCHEMBL26700919 | 0.83 | HPGD (0.45) | HPGDCNR1CNR2TSHRSMN1; SMN2 | |
| SCHEMBL23729309 | 0.82 | HPGD (0.49) | HPGDCNR1CNR2TSHRSMN1; SMN2 | |
| SCHEMBL24253181 | 0.82 | TSHR (0.49) | HPGDCNR1CNR2TSHRLMNA | |
| SCHEMBL26709264 | 0.81 | HPGD (0.48) | HPGDCNR1CNR2TSHRSMN1; SMN2 | |
| SCHEMBL23729792 | 0.80 | SMN1; SMN2 (0.56) | TSHRSMN1; SMN2ALDH1A1CASP2MEN1 | |
| SCHEMBL18707765 | 0.80 | HPGD (0.49) | HPGDCNR1CNR2TSHRSMN1; SMN2 | |
| SCHEMBL24429252 | 0.79 | HPGD (0.47) | HPGDCNR1CNR2TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155321-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |