SCHEMBL23729313

SCHEMBL23729313

CC(C)CCOCCCC(=O)NCCCCCCNC(C)C

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.46
CNR1 P21554 3/20 0.43
CNR2 P34972 2/20 0.43
TSHR P16473 1/20 0.41
NAMPT P43490 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.39
CASP2 P42575 1/20 0.39
LMNA P02545 2/20 0.39
PKM P14618 1/20 0.39
ADRB2 P07550 1/20 0.37
ADRB1 P08588 1/20 0.37
NAAA Q02083 1/20 0.37
ALDH1A1 P00352 1/20 0.37
HTT P42858 1/20 0.36
GLP1R P43220 3/20 0.36
FAAH O00519 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26709264 0.91 HPGD (0.48) HPGDCNR1CNR2TSHRNAMPT
SCHEMBL23320108 0.87 TSHR (0.47) HPGDCNR1CNR2TSHRNAMPT
SCHEMBL26708162 0.87 TSHR (0.42) HPGDCNR1CNR2TSHRNAMPT
SCHEMBL26708617 0.87 TSHR (0.42) HPGDCNR1CNR2TSHRNAMPT
SCHEMBL26700763 0.87 TSHR (0.42) HPGDCNR1CNR2TSHRNAMPT
SCHEMBL25480495 0.86 CNR1 (0.44) HPGDCNR1CNR2TSHRNAMPT
SCHEMBL23730062 0.86 HPGD (0.46) HPGDCNR1CNR2TSHRNAMPT
SCHEMBL26034458 0.86 TSHR (0.41) HPGDCNR1CNR2TSHRSMN1; SMN2
SCHEMBL23730071 0.85 SMN1; SMN2 (0.53) HPGDTSHRSMN1; SMN2CASP2NAAA
SCHEMBL26708616 0.85 TSHR (0.44) HPGDTSHRSMN1; SMN2CASP2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021155321-A2 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. (US) 2021-08-05 WO disclosed