Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | GLP1R | P43220 | 8/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CASP2 | P42575 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17697227 | 0.93 | CES2 (0.49) | CES2GLP1RTSHRFAAHRECQL | |
| SCHEMBL23729785 | 0.91 | SMN1; SMN2 (0.50) | CES2GLP1RSMN1; SMN2TSHR | |
| SCHEMBL24484088 | 0.91 | CES2 (0.51) | CES2GLP1RTSHRCNR1FAAH | |
| SCHEMBL22247042 | 0.91 | CES2 (0.51) | CES2GLP1RSMN1; SMN2TSHRCNR1 | |
| SCHEMBL26020180 | 0.89 | CES2 (0.54) | CES2GLP1RCNR1FAAHCASP2 | |
| SCHEMBL16350546 | 0.89 | CES2 (0.50) | CES2GLP1RTSHRFAAHRECQL | |
| SCHEMBL15259286 | 0.88 | CES2 (0.57) | CES2GLP1RFAAHCASP2ENPP2 | |
| SCHEMBL17697369 | 0.88 | CES2 (0.57) | CES2GLP1RFAAHCASP2ENPP2 | |
| SCHEMBL12807256 | 0.87 | CES2 (0.46) | CES2GLP1RSMN1; SMN2TSHRFAAH | |
| SCHEMBL15259279 | 0.87 | CES2 (0.46) | CES2GLP1RSMN1; SMN2TSHRFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155321-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |