Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1856831 | 0.74 | — | — | |
| SCHEMBL14643890 | 0.71 | METAP1 (0.33) | TSHR | |
| SCHEMBL13906771 | 0.71 | METAP1 (0.33) | TSHR | |
| SCHEMBL27591899 | 0.70 | — | — | |
| SCHEMBL24227175 | 0.70 | — | — | |
| SCHEMBL25777392 | 0.69 | — | — | |
| SCHEMBL1658151 | 0.68 | TSHR (0.33) | TSHR | |
| SCHEMBL4214133 | 0.68 | TRPA1 (0.39) | TSHR | |
| SCHEMBL4214137 | 0.68 | TRPA1 (0.39) | TSHR | |
| SCHEMBL28227797 | 0.68 | TSHR (0.33) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155321-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |