SCHEMBL23729679

SCHEMBL23729679

CCCn1c(=O)c2c(C)c(C(=O)C3=C(O)CCCC3=O)ccc2n(CC(F)F)c1=O

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HPD P32754 8/20 0.33
CNR2 P34972 3/20 0.33
ADORA2B P29275 3/20 0.32
ADORA2A P29274 2/20 0.32
CNR1 P21554 1/20 0.31
ADORA1 P30542 1/20 0.30
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
GAA P10253 1/20 0.30
HPGD P15428 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23730109 0.89 HPD (0.34) HPDCNR2ADORA2BADORA2ACNR1
SCHEMBL23730135 0.89 HPD (0.40) HPDCNR2ADORA2BADORA2AKDM4E
SCHEMBL23729681 0.89 HPD (0.36) HPDCNR2ADORA2BADORA2ACNR1
SCHEMBL23730108 0.88 HPD (0.36) HPDADORA2BADORA2AKDM4EALDH1A1
SCHEMBL23729332 0.87 CNR2 (0.35) HPDCNR2KDM4EALDH1A1GAA
SCHEMBL23729701 0.86 HPD (0.39) HPDCNR2ADORA2BADORA2ASMN1; SMN2
SCHEMBL23729330 0.85 CNR2 (0.39) HPDCNR2
SCHEMBL23729337 0.85 HPD (0.33) HPDCNR2ADORA2BADORA2A
SCHEMBL23729336 0.84 CNR2 (0.36) HPDCNR2ADORA2BADORA2AADORA1
SCHEMBL23730150 0.83 CNR2 (0.32) HPDCNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3858818-A1 TRIKETONE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF, AND HERBICIDE Shandong Cynda Chemical Co., LTD. (CN) 2021-08-04 EP disclosed