Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
| ▸ | PHGDH | O43175 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9801142 | 0.84 | GAA (0.41) | GAAPAOXKDM4EGLAMGLL | |
| SCHEMBL24319340 | 0.84 | GAA (0.41) | GAAPAOXKDM4EGLAMGLL | |
| SCHEMBL25304200 | 0.84 | GAA (0.41) | GAAPAOXKDM4EGLAMGLL | |
| SCHEMBL16304066 | 0.80 | GAA (0.47) | GAAPAOXKDM4EGLALMNA | |
| SCHEMBL15936176 | 0.77 | GAA (0.37) | GAAPAOXKDM4EGLALMNA | |
| SCHEMBL438181 | 0.77 | PAOX (0.38) | GAAPAOXTP53ALDH1A1SIGMAR1 | |
| SCHEMBL9319178 | 0.76 | HRH3 (0.38) | LMNATP53 | |
| SCHEMBL22824638 | 0.73 | PAOX (0.35) | GAAPAOXLMNAALDH1A1SIGMAR1 | |
| SCHEMBL3599195 | 0.73 | PAOX (0.35) | GAAPAOXLMNAALDH1A1SIGMAR1 | |
| SCHEMBL25821392 | 0.73 | PAOX (0.35) | GAAPAOXKDM4ELMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155321-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |