Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | PHGDH | O43175 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24319340 | 1.00 | GAA (0.41) | GAAPAOXKDM4EGLAMGLL | |
| SCHEMBL25304200 | 1.00 | GAA (0.41) | GAAPAOXKDM4EGLAMGLL | |
| SCHEMBL9319178 | 0.92 | HRH3 (0.38) | HRH3TP53SMN1; SMN2 | |
| SCHEMBL23729784 | 0.84 | GAA (0.38) | GAAPAOXKDM4EGLAMGLL | |
| SCHEMBL9801809 | 0.83 | DRD2 (0.39) | HRH3SIGMAR1SMN1; SMN2 | |
| SCHEMBL9801052 | 0.83 | KMT2A (0.48) | GAAKDM4EALDH1A1TP53POLB | |
| SCHEMBL9801680 | 0.83 | KDM4E (0.35) | KDM4EHRH3SIGMAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL438181 | 0.82 | PAOX (0.38) | GAAPAOXMC4RSIGMAR1ALDH1A1 | |
| SCHEMBL3271095 | 0.82 | HRH3 (0.46) | HRH3ALDH1A1POLB | |
| SCHEMBL9801327 | 0.81 | ALOX15 (0.59) | HRH3SIGMAR1ALDH1A1TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022047145-A1 | RAPIDLY ACCELERATING FIBROSARCOMA PROTEIN DEGRADING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2022-03-03 | — | — | WO | disclosed |
| EP-2414327-B1 | HETEROCYCLIC COMPOUNDS AS AUTOTAXIN INHIBITORS | MERCK PATENT GMBH (DE) | 2014-11-19 | — | — | EP | disclosed |
| US-8841324-B2 | Heterocyclic compounds as autotaxin inhibitors | MERCK PATENT GMBH (DE) | 2014-09-23 | — | — | US | disclosed |
| US-4992150-A | Telomer with alpha-olefin;oil and fuel additive | NIPPON OIL CO, LTD. (JP) | 1991-02-12 | — | — | US | disclosed |