Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GLP1R | P43220 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25976736 | 0.89 | MEN1 (0.45) | BCHEACHEMEN1KMT2AFAAH | |
| SCHEMBL26429195 | 0.85 | MEN1 (0.45) | MEN1KMT2ATSHRRECQLGLP1R | |
| SCHEMBL24470294 | 0.85 | MEN1 (0.45) | MEN1KMT2AFAAHTSHRRECQL | |
| SCHEMBL25029948 | 0.85 | MEN1 (0.40) | MEN1KMT2ATSHRGLP1RALDH1A1 | |
| SCHEMBL21501564 | 0.84 | GLP1R (0.45) | MEN1KMT2AFAAHTSHRRECQL | |
| SCHEMBL26700490 | 0.83 | LMNA (0.40) | MEN1KMT2ATSHRHTTALDH1A1 | |
| SCHEMBL24674803 | 0.82 | MEN1 (0.45) | MEN1KMT2AGLP1RALDH1A1 | |
| SCHEMBL25913029 | 0.82 | MEN1 (0.45) | MEN1KMT2AGLP1RALDH1A1 | |
| SCHEMBL22856474 | 0.82 | KMT2A (0.53) | BCHEACHEMCL1CHRNB2CHRNB4 | |
| SCHEMBL25122775 | 0.82 | KMT2A (0.53) | BCHEACHEMCL1CHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155321-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |