Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GLP1R | P43220 | 8/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.30 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
| ▸ | CA4 | P22748 | 2/20 | 0.30 |
| ▸ | CA9 | Q16790 | 2/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23729570 | 0.84 | MEN1 (0.41) | MEN1KMT2AAPPCA12CA1 | |
| SCHEMBL26700492 | 0.84 | MEN1 (0.41) | MEN1KMT2AAPPCA12CA1 | |
| SCHEMBL26707240 | 0.83 | MEN1 (0.42) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL23729600 | 0.81 | MEN1 (0.44) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL21106543 | 0.80 | MEN1 (0.47) | MEN1KMT2AGLP1RCA12CA1 | |
| SCHEMBL25831170 | 0.80 | KMT2A (0.45) | MEN1KMT2AGLP1R | |
| SCHEMBL25029532 | 0.77 | MEN1 (0.44) | MEN1KMT2AGLP1R | |
| SCHEMBL21026058 | 0.77 | ALDH1A1 (0.35) | MEN1KMT2A | |
| SCHEMBL21106879 | 0.76 | KMT2A (0.56) | MEN1KMT2AGLP1RCA2 | |
| SCHEMBL22374969 | 0.76 | SMN1; SMN2 (0.41) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155321-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |