SCHEMBL23730461

SCHEMBL23730461

C=C(/C=C(/Br)CC)C(N)=O

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.35
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20850153 0.76 TDP1 (0.42) TDP1ALDH1A1TSHR
SCHEMBL9864274 0.69
SCHEMBL9864277 0.69
SCHEMBL21894667 0.69
SCHEMBL23709595 0.68 TDP1 (0.43) TDP1
SCHEMBL19087302 0.68 TDP1 (0.39) TDP1ALDH1A1TSHR
SCHEMBL22167854 0.67
SCHEMBL18593919 0.67 TDP1 (0.42) TDP1ALDH1A1TSHR
SCHEMBL19111919 0.65 TDP1 (0.36) TDP1
SCHEMBL6131240 0.65 MEN1 (0.42) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021153168-A1 COMPOUND, LIGHT-EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING ELEMENT 国立大学法人京都大学 2021-08-05 WO disclosed