SCHEMBL23709595

SCHEMBL23709595

C=C(/C=C(\C)C(=O)O)C(N)=O

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.43
LDHA P00338 1/20 0.36
LDHB P07195 1/20 0.36
PARP1 P09874 1/20 0.33
PARP15 Q460N3 1/20 0.33
PARP10 Q53GL7 1/20 0.33
LMNA P02545 1/20 0.32
ALOX15 P16050 1/20 0.32
BLM P54132 1/20 0.32
PMP22 Q01453 1/20 0.32
CYP2C9 P11712 1/20 0.32
PTGS1 P23219 1/20 0.31
AKR1C3 P42330 1/20 0.31
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL137715 0.82 PTGS1 (0.34) TDP1LMNACYP2C9PTGS1AKR1C3
SCHEMBL15298996 0.82 PTGS1 (0.34) TDP1LMNACYP2C9PTGS1AKR1C3
SCHEMBL8059991 0.80
SCHEMBL28861159 0.80 PTGS1 (0.33) CYP2C9PTGS1AKR1C3MAPT
Methacrylic Acid SCHEMBL4296926 0.78 TDP1 (0.33) TDP1CYP2C9PTGS1AKR1C3MAPT
SCHEMBL6131240 0.77 MEN1 (0.42) TDP1LDHABLM
SCHEMBL21894667 0.77
SCHEMBL3847324 0.76 ALDH1A1 (0.39) LMNAALOX15CYP2C9PTGS1AKR1C3
SCHEMBL22369407 0.76 ALDH1A1 (0.44) TDP1
SCHEMBL6864943 0.76 ALDH1A1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11079634-B2 Liquid crystal display device and method for manufacturing same SHARP KABUSHIKI KAISHA (JP) 2021-08-03 US disclosed